Ingredient Record

2,3,5,6-Tetramethylpyrazine

Aromatic compound providing nutty, roasted, and earthy notes.

CAS 1124-11-4

HigherBar policy

No policy

No HigherBar policy on this ingredient.

Regulatory status

Approved in 4 of 7 tracked registries, no published record in 3.

See the status of each registry, with sources

What It Is

This methylated pyrazine is found in roasted foods, cocoa, and coffee and provides earthy, nutty, and roasted notes. It is used at parts-per-million levels to enhance aroma in beverages, confectionery, and baked goods. The compound is approved in multiple jurisdictions as a food flavoring.

Regulatory Record

What each registry publishes about 2,3,5,6-tetramethylpyrazine.

Every row comes from a published regulator source, linked so you can read it yourself. "Prohibited" means a regulator has affirmatively banned it; "not authorized" means it has never been cleared for that use there. The two are not the same thing, so we never collapse them.

Approved in 4 of 7 tracked registries, no published record in 3. Last verified Oct 1, 2026.

Published regulatory status for 2,3,5,6-Tetramethylpyrazine, one row per registry.
RegistryStatusPublished record
United States (FDA)ApprovedgrasTechnical effect: FLAVORING AGENT OR ADJUVANTNo effective date published · Last verified Oct 1, 2026View the source document
European Union (EFSA)ApprovedflavorNo effective date published · Last verified Oct 1, 2026View the source document
United Kingdom (FSA)ApprovedflavorEffective Dec 31, 2020 · Last verified Oct 1, 2026View the source document
Codex Alimentarius (JECFA)No published dataOur sources hold no evidenced record here. That is not a clearance and not a ban.
Japan (CAA)Approvedfood additiveNo effective date published · Last verified Oct 1, 2026View the source document
Australia & New Zealand (FSANZ)No published dataOur sources hold no evidenced record here. That is not a clearance and not a ban.
Canada (Health Canada)No published dataOur sources hold no evidenced record here. That is not a clearance and not a ban.

We publish only evidenced regulatory rows, each with its source. Coverage is uneven across registries, and a missing row is reported as missing.

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